Anidulafungin package insert pdf file

Anidulafungin vicuron pharmaceuticals is a new echinocandin antifungal with potent activity against aspergillus and candida spp. Eraxis fda prescribing information, side effects and uses. Cancidas caspofungin acetate for injection, for intravenous use. Anidulafungin is an echinocandin, a class of antifungal drugs that inhibits the synthesis of 1,3. Chemical and physical inuse stability of the infusion solution has been demonstrated for 48 hours at 25.

Find patient medical information for anidulafungin intravenous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Analysis and proposal for interpretive mic breakpoints. Eraxis anidulafungin for injection, prescribing information. These highlights do not include all the information needed to use advate safely and effectively. The recommended dose is a single 100 mg loading dose of eraxis on day 1, followed by 50 mg daily dose thereafter. Information from its description page there is shown below. Eraxis anidulafungin dosing, indications, interactions. Eraxis anidulafungin dosage and administration pfizer. Drug interaction studies were performed with anidulafungin and other medicinal products likely to be coadministered. The development of echinocandins, the first class of antifungals to target the fungal cell wall. Anidulafungin is a noncompetitive inhibitor of 1,3betad. Dosage in pediatric patients 3 months to 17 years of age 2.

Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for delsym dextromethorphan. Pdf anidulafungin and its role in candida infections researchgate. Patients should be treated for a minimum of 14 days and for at least 7 days following resolution of symptoms. Eligible patients can register for valuable savings offers for nearly 40 brand name medications. Final package insert for eraxis anidulafungin for injection in this study, of 280 patients tested, 237 84. Pdf correlation of mic with outcome for candida species. No dosage adjustment of either drug is required when coadministered. Final package insert for eraxis anidulafungin for injection. In both groups the median time to resolution of symptoms was 5 days and the median duration of therapy was 14 days. Eraxis infusion solution can be stored at temperatures up to 25c 77f for up to 48 hours or stored frozen for at least 72 hours. Cancidas caspofungin acetate for injection, for intravenous use, prescribing information. The echinocandins have been a welcome addition to this group, with the latest being anidulafungin. In a study in which 35 healthy subjects received a single oral dose of 5 mg tacrolimus on day 1, 100 mgday maintenance dose of anidulafungin following a 200 mg loading dose on days 4 to 12 and both in combination on day, the steady state c max and auc of anidulafungin and tacrolimus were not significantly altered by coadministration see drug interactions 7.

Package insert for eraxis anidulafungin for injection rx. Ecalta 100 mg powder for concentrate for solution for infusion. There are several lines of evidence to support anidulafungin s role as primary therapy for the treatment of invasive candidiasis in nonneutropenic patients, and as alternative therapy to fluconazole in patients with esophageal candidiasis with azole intolerance or triazoleresistant candida. Correlation of mic with outcome for candida species tested against caspofungin, anidulafungin, and micafungin. The primary endpoint was endoscopic outcome at end of therapy eot. The recommended dose is a single 200 mg loading dose of eraxis on day 1, followed by 100 mg daily dose thereafter.

Anidulafungin in the treatment of invasive fungal infections. The pharmacokinetics of intravenous anidulafungin in adult intensive care unit icu. Pharmacokinetics of anidulafungin in critically ill patients with. Fda approved anidulafungin in febru ary 2006 for the. Pfizer rxpathways connects eligible patients to a range of assistance programs to help them access their pfizer prescriptions. Duration of treatment should be based on the patients clinical response. These highlights do not include all the information needed to use cuvitru safely and effectively. Package insert for eraxis anidulafungin for injection in this study, of 280 patients tested, 237 84. No dosage adjustment of either medicinal product is recommended when anidulafungin is coadministered with ciclosporin, voriconazole or tacrolimus, and no. Ecalta, innanidulafungin european medicines agency. Anidulafungin does not require dosage adjustment in subjects with varying degrees of.